Prenatal sex discernment

Prenatal sex discernment is the prenatal testing for discerning the sex of a fetus before birth.

Contents

Methods

Prenatal sex discernment can be performed by preimplantation genetic diagnosis before conception.

The earliest post-implantation test is to take a blood sample from the mother and test on the small amount of fetal DNA that can be found within it. A meta-analysis published in 2011 found that such tests are reliable more than 98% of the time, as long as they are taken after the seventh week of pregnancy.[1][2]

Obstetric ultrasonography, either transvaginally or transabdominally, can check for the sagittal sign as a marker of fetal sex. It can be performed between 65 and 69 days from fertilization (week 12 of gestational age), where it gives a result in 90% of cases - a result that is correct in approximately ¾ of cases, according to a study from 2001.[3] Accuracy for males is approximately 50% and for females almost 100%. When performed later, after 70 days from fertilization (at week 13 of gestational age), it gives an accurate result in almost 100% of cases.[3]

Applications

Potential applications of prenatal sex discernment include:

Legal Status

Prenatal sex determination was banned in India in 1994, under the Pre-conception and Prenatal Diagnostic Techniques (Prohibition of Sex Selection) Act.[4] The act aims to prevent sex-selective abortion, which, according to the Indian Ministry of Health and Family Welfare, "has its roots in India’s long history of strong patriarchal influence in all spheres of life".[5]

References

  1. ^ Devaney SA, Palomaki GE, Scott JA, Bianchi DW (2011). "Noninvasive Fetal Sex Determination Using Cell-Free Fetal DNA". JAMA 306 (6): 627–636. doi:10.1001/jama.2011.1114. PMID 21828326. 
  2. ^ Roberts, Michelle (10 August 2011). "Baby gender blood tests 'accurate'". BBC News Online. http://www.bbc.co.uk/news/health-14457670. 
  3. ^ a b Mazza V, Falcinelli C, Paganelli S, et al. (June 2001). "Sonographic early fetal gender assignment: a longitudinal study in pregnancies after in vitro fertilization". Ultrasound Obstet Gynecol 17 (6): 513–6. doi:10.1046/j.1469-0705.2001.00421.x. PMID 11422974. 
  4. ^ "Pre-conception and Prenatal Diagnostic Techniques (Prohibition of Sex Selection) Act". http://pndt.gov.in/writereaddata/mainlinkFile/File50.pdf. Retrieved 2010-11-27. 
  5. ^ "Indian Health Ministry's FAQ page on the PNDT Act". http://pndt.gov.in/writereaddata/mainlinkfile/File53.pdf. Retrieved 2010-11-27.